Московский семинар по биоинформатике prof. Dr. Edgar Wingender «Constructions and Analysis of Gene Regulatory Networks»
21 March 2013, MoscowRubrics: Seminar | Biology, Biotechnologies Activity URL: http://www.rtcb.iitp.ru/msb/Index.htmDescription:Четверг, 21 марта 2013 года, 18:00, Москва, МГУ, лабораторный корпус «Б».
Тема заседания — доклад prof. Dr. Edgar Wingender, University Medical Center Goettingen and geneXplain GmbH, Germany;
«Constructions and Analysis of Gene Regulatory Networks»
Gene regulatory networks comprising transcriptional and post-transcriptional events may provide a useful tool for characterizing regulatory processes of a cell with systems biological approaches. Using bioinformatic approaches for two independent criteria (predicted affinity and multi-genome conservativity), we have constructed the core of a transcriptional network for human cells. This network was expanded (a) by paralogous TF-target gene relations, based on a comprehensive transcription factor classification, and (b) by predicted and known microRNA-target gene relations. From the resulting gene regulatory reference network, a number of tissue-specific subnetworks could be extracted. They revealed structural particularities that seem to be characteristic for the different tissues.
Рабочий язык семинара — английский.
Адрес:
Москва, МГУ, лабораторный корпус «Б» (факультет биоинженерии и биоинформатики), комната 221 (2 этаж, направо по коридору).
Проезд: Станция метро Университет, автобусы 187, 260, 130, 103, 113, 661, 47 или троллейбус 34 до остановки: «Улица Менделеевская».
Схема проезда